However, at least he had the brains to just ask about it nicely, make it clear that the question was in the context of the art of a TV show, and wait for an answer - that's a lot better than most of the commentary about anyone who isn't ashamed of being naked...
If the transcript is accurate, I'm now also not a fan of Judd Apatow (as a disclaimer, I've never watched Girls and don't really know anything more about Apatow than he works on that show) - it's not at all helpful to take a question from someone who's being curious rather than openly hostile, twist it all out of proportion and then tell the guy he's being sexist, misogynist and offensive. Leaping down someone's throat straight off the bat like that is perhaps the fastest possible way to stophaving a conversation and start having an argument.
If he'd been critical of Dunham's nudity, or made a gender thing out of it, or something like that, sure. Tell him he's being an arsehole and then, if necessary, explain why. If it's really clear that he is, then maybe don't bother explaining if it's hassle you don't want -and shouldn't be expected - to deal with.
However, this just seemed like an honest question from a guy who wanted to understand a production decision better. I can't see anything remotely misogynistic or sexist about that, and treating it like it was instead of engaging with it properly a) demeans the efforts of people (Lena Dunham herself included) who try to fight properly bad acts and attitudes from actually bad people and b) just turns potential allies in that fight into neutrals at best. It's counterproductive and I want to see less of it. Gender equality lost out here, and that's disappointing.
Just to be clear, I do think it's a bit sad that Molloy couldn't look further than production decisions when thinking about a naked person in a TV show. However, that's his job, and I think it's also encouraging that he thought to try to find out more and expand his horizons a bit, to question something that didn't fit with his own experiences and to just ask instead of throwing toys out of the pram. Apatow then proceeds to throw his toys out of the pram, and it's just lucky that Molloy was decent enough to take it calmly and keep trying to understand even in the face of getting (metaphorically) shouted at.
I've just realised that this has turned into a wall of text, so I'm sorry about that. It's just that this kind of thing has ramifications for us as a group as well: if I met someone extremely prudish, who thought that the naked human body was weird, embarrassing and offensive (which is significantly worse than the position Molloy took, which seemed basically neutral), but was prepared to talk to me and ask me about my views and why I held them, would I make that person more or less accepting of my own views, and hence likely to change their own, by ranting at them about how they're so condescending and bigoted and just wrong about everything and it's so obvious and they need to JUST. STOP. NOW, or by engaging with them calmly and politely? I think the latter, and I think that's borne out by the absolutely brilliant tales of black Americans talking to and even befriending KKK members, and showing them the error of their ways (almost put 'showing them the light' then; realised it wasn't the most appropriate metaphor I've ever thought of) through being rational and friendly rather than confrontational.
I'm not saying that being confrontational is never the right answer - there are heaps of shitty people out there who have a warped mindset about women and their bodies, and sometimes calling them out on that and telling them exactly where to go is both a brave and brilliant thing to do. But at least to me, that's not what this is. This feels like an attempt at using a big soapbox to humiliate and bully someone smaller who you could have helped instead. And I think that just won't get us anywhere.